An Interactive Visualisation for Investigating DNA Sequence Information

Rutherford, P., Churcher, C. and McCallum, J.

    The sequence of nucleotides that makes up a DNA molecule encodes the characteristics of living things. Bioinformatics offers sophisticated methods to search for and compare nucleotide and protein sequences. Having found a sequence, however, it is useful to be able to quickly obtain an overview of its features. This can be difficult in the standard textual format used to represent sequences. In this paper we offer a simple facility whereby a scientist can interactively scan for recurring patterns in the sequence and investigate reading frames, variable regions, positions of particular codons and other features. It is intended that this be incorporated as a tool or component into public domain bioinformatics applications. The visualisations are useful for sequences up to 2000 base pairs.
Cite as: Rutherford, P., Churcher, C. and McCallum, J. (2004). An Interactive Visualisation for Investigating DNA Sequence Information. In Proc. Australasian Symposium on Information Visualisation, (invis.au'04), Christchurch, New Zealand. CRPIT, 35. Churcher, N. and Churcher, C., Eds. ACS. 101-107.
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